AMG-337

DB15639InvestigationalSmall molecule

AMG-337 is under investigation in clinical trial NCT03147976 (QUILT-3.036: AMG 337 in Subjects With Advanced or Metastatic Solid Tumors).

Mechanism: Pharmacologically active on Hepatocyte growth factor receptor
Curator reviewed
Formula / weight: C₂₃H₂₂FN₇O₃ · 463.473 g/mol (avg)
Code names: AMG-337

Resolves to

Compound

Structure

InChIKeyDWHXUGDWKAIASB-CQSZACIVSA-NSMILESCOCCOC1=CC2=C(C=CN([C@H](C)C3=NN=C4N3C=C(C=C4F)C3=CN(C)N=C3)C2=O)N=C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

6Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with AMG-337, and which of those have an active Phase 3 trial?

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