Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more... Its higher affinity to the estrogen receptor, higher anti-estrogenic to estrogenic ratio, more effective inhibition of cell growth and division in estrogen receptor-positive cell lines, and lower toxicity give it theoretical advantages over tamoxifen in...
- Mechanism
- Curator reviewed
Pharmacologically active on Estrogen receptor
- Formula / weight
- C26H29NO2 · 387.523 g/mol (avg)
Resolves to
ZQZFYGIXNQKOAV-OCEACIFDSA-NSMILESCC\C(=C(\C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC(O)=C1)C1=CC=CC=C1What you can answer from here — as of June 15, 2026
Which drugs share a target with Droloxifene, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account