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Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
- Mechanism
- Curator reviewed
pGSN also enhances bacterial uptake and death by macrophages. It has positive effects on the immune system as it boosts clearing of pathogens and modulates inflammatory reactions; often pGSN is consumed in both serious infectious and non-infectious conditions. Its physiological effects thus make it a potential candidate for severe acute respiratory syndrome (ARDS) associated with COVID-19, as administration of recombinant protein is thought to supplement depleted levels of pGSN.
- Also known as
- Gelsolin · Gelsolin recombinant · pGSN · Plasma gelsolin · Recombinant human gelsolin
- Code names
- Recombinant Human Plasma Gelsolin
Resolves to
What you can answer from here — as of April 23, 2025
Which drugs share a target with Recombinant human plasma gelsolin, and which of those have an active Phase 3 trial?