Sodium metabisulfite

Explore a selection of our essential drug information below, or:

CREATE FREE ACCOUNT

Full Drug Profiles

Unlock enhanced features & extensive drug insights, including detailed interaction data & regulatory status. Create a free account.

SUBSCRIBERECOMMENDED FOR PHARMA

Data Packages

Explore the full scope of our drug knowledge tailored for pharmaceutical research needs in our data library. Learn more.

Identification

Summary

Sodium metabisulfite is an ingredient used in products to treat dehydration and replace electrolytes.

Generic Name

Sodium metabisulfite

DrugBank Accession Number

DB15842

Background

Not Available

Type

Small Molecule

Groups

Experimental

Structure

Download

MOLSDFPDBSMILESInChI

Similar Structures

Structure for Sodium metabisulfite (DB15842)

×

Close

Weight

Average: 190.09
Monoisotopic: 189.89825401

Chemical Formula

Na₂O₅S₂

Synonyms

• Disodium pentaoxodisulfate
• Disodium pyrosulfite
• Disodium pyrosulphite
• Disulfurous acid, disodium salt
• Sodium metabisulfite
• Sodium metabisulphite
• Sodium pyrosulfite
• Sodium pyrosulphite

External IDs

• E-223
• INS NO.223
• INS-223

Unlock the secrets to drugging the undruggable

Discover how groundbreaking research is turning "undruggable" targets into therapeutic opportunities.

Download eBook

Unlock the secrets to drugging the undruggable

Download eBook

Pharmacology

Indication

Not Available

Reduce drug development failure rates

Build, train, & validate machine-learning models
with evidence-based and structured datasets.

See how

Build, train, & validate predictive machine-learning models with structured datasets.

See how

Associated Conditions

Indication Type	Indication	Combined Product Details	Approval Level	Age Group	Patient Characteristics	Dose Form
Used in combination to treat	Dehydration	Combination Product in combination with: Sodium acetate (DB09395), Potassium chloride (DB00761), D-glucose (DB01914), Dipotassium phosphate (DB09414), Sodium chloride (DB09153)	••••••••••••	•••••		•••••••••• ••••••••
Used in combination to treat	Potassium deficiency	Combination Product in combination with: Dipotassium phosphate (DB09414), Sodium chloride (DB09153), D-glucose (DB01914), Sodium acetate (DB09395), Potassium chloride (DB00761)	••••••••••••	•••••		•••••••••• ••••••••
Used in combination to treat	Potassium deficiency	Combination Product in combination with: Potassium chloride (DB00761), Dipotassium phosphate (DB09414), Sodium acetate (DB09395), Sodium chloride (DB09153), D-glucose (DB01914)	••••••••••••	•••••		•••••••••• ••••••••
Used in combination to treat	Mild metabolic acidosis	Combination Product in combination with: Potassium chloride (DB00761), Sodium chloride (DB09153), Sodium acetate (DB09395), D-glucose (DB01914), Dipotassium phosphate (DB09414)	••••••••••••	•••••		•••••••••• ••••••••

Create Account

Contraindications & Blackbox Warnings

Prevent Adverse Drug Events Today

Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.

Learn more

Avoid life-threatening adverse drug events with our Clinical API

Learn more

Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

Improve decision support & research outcomes

With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!

See the data

Improve decision support & research outcomes with our structured adverse effects data.

See a data sample

Toxicity

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs

Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Not Available

Food Interactions

Not Available

Products

Drug product information from 10+ global regions

Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.

Access now

Access drug product information from over 10 global regions.

Access now

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
EUROPERSOL WITH DEXTROSE 1.5% PERITONEAL DIALYSIS SOLUTION	Sodium metabisulfite (30 mg/100ml) + Calcium chloride dihydrate (25.7 mg/100ml) + D-glucose monohydrate (1.5 g/100ml) + Sodium lactate (392 mg/100ml) + Magnesium chloride hexahydrate (15.2 mg/100ml) + Sodium chloride (550 mg/100ml)	Solution	Intraperitoneal	JOYSON PTE. LTD.	1998-10-14	Not applicable
EUROPERSOL WITH DEXTROSE 4.25% PERITONEAL DIALYSIS SOLUTION	Sodium metabisulfite (30 mg/100ml) + Calcium chloride dihydrate (25.7 mg/100ml) + D-glucose monohydrate (4.25 g/100ml) + Sodium lactate (392 mg/100ml) + Magnesium chloride hexahydrate (15.2 mg/100ml) + Sodium chloride (550 mg/100ml)	Solution	Intraperitoneal	JOYSON PTE. LTD.	1998-10-14	Not applicable
NEOFLEKS IZOPLEN-M % 5 DEKSTROZLU DENGELI ELEKTROLIT IÇEREN INFÜZYON IÇIN ÇÖZELTI 1000 ML SETLI	Sodium metabisulfite (0.21 g/L) + D-glucose monohydrate (55 g/L) + Dipotassium phosphate (1.3 g/L) + Potassium chloride (1.5 g/L) + Sodium acetate (2.8 g/L) + Sodium chloride (0.91 g/L)	Solution	Intravenous	TURKTIPSAN SAĞLIK TURİZM EĞİTİM VE TİC. A.Ş.	2011-06-07	Not applicable
NEOFLEKS IZOPLEN-M % 5 DEKSTROZLU DENGELI ELEKTROLIT IÇEREN INFÜZYON IÇIN ÇÖZELTI 1000 ML SETSIZ	Sodium metabisulfite (0.21 g/L) + D-glucose monohydrate (55 g/L) + Dipotassium phosphate (1.3 g/L) + Potassium chloride (1.5 g/L) + Sodium acetate (2.8 g/L) + Sodium chloride (0.91 g/L)	Solution	Intravenous	TURKTIPSAN SAĞLIK TURİZM EĞİTİM VE TİC. A.Ş.	2011-06-07	Not applicable
NEOFLEKS IZOPLEN-M % 5 DEKSTROZLU DENGELI ELEKTROLIT IÇEREN INFÜZYON IÇIN ÇÖZELTI 500 ML SETLI	Sodium metabisulfite (0.21 g/L) + D-glucose monohydrate (55 g/L) + Dipotassium phosphate (1.3 g/L) + Potassium chloride (1.5 g/L) + Sodium acetate (2.8 g/L) + Sodium chloride (0.91 g/L)	Solution	Intravenous	TURKTIPSAN SAĞLIK TURİZM EĞİTİM VE TİC. A.Ş.	2011-06-07	Not applicable

Categories

Drug Categories

• Anions
• Autonomic Agents
• Bronchoconstrictor Agents
• Electrolytes
• Ions
• Peripheral Nervous System Agents
• Pharmaceutic Aids
• Respiratory System Agents
• Sulfur Compounds

Classification

Not classified

Affected organisms

Not Available

Chemical Identifiers

UNII

4VON5FNS3C

CAS number

7681-57-4

InChI Key

HRZFUMHJMZEROT-UHFFFAOYSA-L

InChI

InChI=1S/2Na.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2

IUPAC Name

disodium sulfinatosulfonate

SMILES

[Na+].[Na+].[O-]S(=O)S([O-])(=O)=O

References

General References

1. TITCK Product Information: NEOFLEKS IZOPLEN-M (D-glucose monohydrate, dipotassium phosphate, potassium chloride, sodium acetate, sodium chloride, sodium metabisulfite) injection [Link]

External Links

ChemSpider

571015

RxNav

36696

ChEBI

114786

ChEMBL

CHEMBL2016976

Wikipedia

Sodium_metabisulfite

Clinical Trials

Clinical Trials

Clinical Trial & Rare Diseases Add-on Data Package

Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package

Phase	Status	Purpose	Conditions	Count	Start Date	Why Stopped	100+ additional columns
Unlock 175K+ rows when you subscribe.View sample data
1, 2	Not Yet Recruiting	Treatment	Calcinosis / Systemic Sclerosis (SSc)	1	somestatus	stop reason	just information to hide

Unlock 75,000+ rows when you subscribe

Explore data packages curated & structured to speed up your pharmaceutical research

View Sample Data

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Solution	Intraperitoneal	25.7 mg/100ml
Solution	Intravenous

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
logP	-1.6	Chemaxon
pKa (Strongest Acidic)	-2.7	Chemaxon
Physiological Charge	-2	Chemaxon
Hydrogen Acceptor Count	5	Chemaxon
Hydrogen Donor Count	0	Chemaxon
Polar Surface Area	97.33 Å2	Chemaxon
Rotatable Bond Count	1	Chemaxon
Refractivity	18.73 m3·mol-1	Chemaxon
Polarizability	9.14 Å3	Chemaxon
Number of Rings	0	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Not Available

Chromatographic Properties

Collision Cross Sections (CCS)

Adduct	CCS Value (Å2)	Source type	Source
[M-H]-	118.161974	predicted	DarkChem Lite v0.1.0
[M-H]-	111.25476	predicted	DeepCCS 1.0 (2019)
[M+H]+	113.56268	predicted	DeepCCS 1.0 (2019)
[M+Na]+	120.08003	predicted	DeepCCS 1.0 (2019)

×

Identify potential medication risks

Easily compare up to 40 drugs with our drug interaction checker.

Get severity rating, description, and management advice.

Learn more

Drug created at September 16, 2020 19:12 / Updated at May 14, 2021 01:08