NAV

Testosterone isocaproate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Testosterone isocaproate is a steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis.

Generic Name
Testosterone isocaproate
DrugBank Accession Number
DB16002
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 386.576
Monoisotopic: 386.282095084
Chemical Formula
C25H38O3
Synonyms
Not Available
External IDs
  • 239-307-1
  • NSC-26641
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
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interactions in your software
Beclomethasone dipropionateThe risk or severity of edema formation can be increased when Testosterone isocaproate is combined with Beclomethasone dipropionate.
BetamethasoneThe risk or severity of edema formation can be increased when Testosterone isocaproate is combined with Betamethasone.
Betamethasone phosphateThe risk or severity of edema formation can be increased when Testosterone isocaproate is combined with Betamethasone phosphate.
BudesonideThe risk or severity of edema formation can be increased when Testosterone isocaproate is combined with Budesonide.
CiclesonideThe risk or severity of edema formation can be increased when Testosterone isocaproate is combined with Ciclesonide.
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
SUSTANON 250 INJECTIONTestosterone isocaproate (60 mg/ml) + Testosterone decanoate (100 mg/ml) + Testosterone phenylpropionate (60 mg/ml) + Testosterone propionate (30 mg/ml)InjectionIntramuscularDCH AURIGA SINGAPORE1990-05-31Not applicableSingapore flag
TEST - COMP 250Testosterone isocaproate (60 mg/mL) + Testosterone decanoate (100 mg/mL) + Testosterone phenylpropionate (60 mg/mL) + Testosterone propionate (30 mg/mL)Injection, solutionบริษัท กรุงเทพ ฟาร์มา ดิสทริบิวชั่น จำกัด2018-06-06Not applicableThailand flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
X8ST05GYDM
CAS number
15262-86-9
InChI Key
PPYHLSBUTAPNGT-BKWLFHPQSA-N
InChI
InChI=1S/C25H38O3/c1-16(2)5-10-23(27)28-22-9-8-20-19-7-6-17-15-18(26)11-13-24(17,3)21(19)12-14-25(20,22)4/h15-16,19-22H,5-14H2,1-4H3/t19-,20-,21-,22-,24-,25-/m0/s1
IUPAC Name
(1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl 4-methylpentanoate
SMILES
[H][C@@]12CC[C@H](OC(=O)CCC(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

References

General References
  1. FDA Thailand: Test - Comp 250 (Testosterone Decanoate, Testosterone Isocaproate, Testosterone Phenylpropionate, Testosterone Propionate) Injection [Link]
KEGG Compound
C14663
ChemSpider
201317
BindingDB
50103618
RxNav
75806
ChEBI
35001
ChEMBL
CHEMBL3189011
ZINC
ZINC000004538407
Wikipedia
Testosterone_isocaproate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
InjectionIntramuscular100 mg/ml
Injection, solution
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.000955 mg/mLALOGPS
logP4.36ALOGPS
logP5.68Chemaxon
logS-5.6ALOGPS
pKa (Strongest Acidic)18.52Chemaxon
pKa (Strongest Basic)-4.8Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area43.37 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity111.96 m3·mol-1Chemaxon
Polarizability46.61 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0079-0079000000-0f19f1f614cb7bad3805
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-000i-0009000000-dd05adb70a269a3d2c48
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-000i-2169000000-43bf9e375c87a9cc3623
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0079-0493000000-5c7b09b642aa0cd4a9b0
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0a4i-9001000000-9617f7956d1085c74dee
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0acc-8963000000-309962601e27d8a87a6d
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-203.0103692
predicted
DarkChem Lite v0.1.0
[M-H]-197.56784
predicted
DeepCCS 1.0 (2019)
[M+H]+203.6539692
predicted
DarkChem Lite v0.1.0
[M+H]+199.46326
predicted
DeepCCS 1.0 (2019)
[M+Na]+203.2637692
predicted
DarkChem Lite v0.1.0
[M+Na]+205.24118
predicted
DeepCCS 1.0 (2019)

Drug created at December 10, 2020 21:00 / Updated at May 05, 2021 20:32