Androgen receptor

BE0000132ProteinHumansAR

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (PubMed:19022849). It is acted on by 148 drugs in DrugBank.

Gene name
AR
UniProtKB entry
P10275Swiss-Prot
Cellular location
Nucleus
Residues / weight
920 residues · 99,187 Da
Also known as
DHTR · Dihydrotestosterone receptor · NR3C4 · Nuclear receptor subfamily 3 group C member 4

Resolves to

Protein
UniProtP10275UniProt nameANDR_HUMAN
Gene
HGNCHGNC:644NCBI Gene367GenBank178628GeneCardsAR
Pharmacology
IUPHAR/GtoPdb628KEGGhsa:367
Structure
PDB1E3GPDB1GS4PDB1T5Z
Drugs

What you can answer from here — as of September 07, 2019

148DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
8Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
36GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
587+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Androgen receptor, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In