GSK2798745

DB16033InvestigationalSmall molecule

GSK2798745 is under investigation in clinical trial NCT03372603 (A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough).

Mechanism: Pharmacologically active on Transient receptor potential cation channel subfamily V member 4
Curator reviewed
Formula / weight: C₂₅H₂₈N₆O₃ · 460.538 g/mol (avg)
Code names: GSK-2798745

Resolves to

Compound

UNII63FJ7LF55OCAS1419609-94-1

Structure

InChIKeyURCMKDJBULWNAI-DQEYMECFSA-NSMILESCC(C)(O)C1=NC=C(N=C1)N1C[C@@]2(CCC[C@](C)(CN3C=NC4=C3C=C(C=C4)C#N)C2)OC1=O

Targets

Q9HBA0TRPV4

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

6Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with GSK2798745, and which of those have an active Phase 3 trial?

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