4'-Thio-fac

DB16071InvestigationalSmall molecule

4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and Lymphomas).

Chemical structure of 4'-Thio-fac
Formula / weight
C9H12FN3O3S · 261.27 g/mol (avg)
Also known as
4-Amino-1-[(2R,3S,4S,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrothiophen-2-Yl] Pyrimidin-2(1H)-One
Code names
FF-10502

Resolves to

Compound
UNIIR5B1HX1HUYCAS184302-49-6
Structure
InChIKeyNIDPJRZOVFIBQB-PXBUCIJWSA-NSMILESNC1=NC(=O)N(C=C1)[C@@H]1S[C@H](CO)[C@@H](O)[C@@H]1F
Targets
P06746POLB

What you can answer from here — as of April 23, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1Clinical trialPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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