Exicorilant

DB16162InvestigationalSmall molecule

Exicorilant is under investigation in clinical trial NCT03437941 (Study to Evaluate CORT125281 in Combination With Enzalutamide in Patients With Mcrpc).

Chemical structure of Exicorilant
Formula / weight
C26H23F4N7O3S · 589.57 g/mol (avg)
Code names
CORT-125281

Resolves to

Compound
UNIIGTB859B7K8CAS1781244-77-6ChEMBLCHEMBL4089731
Structure
InChIKeyHWJYJKAURRIWJM-GKVSMKOHSA-NSMILES[H][C@@]12CCN(C[C@]1(CC1=C(C2)N(N=C1)C1=CC=C(F)C=C1)C(=O)C1=CC(=CC=N1)C(F)(F)F)S(=O)(=O)C1=NN(C)N=C1
Targets
P04150NR3C1

What you can answer from here — as of April 23, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Exicorilant, and which of those have an active Phase 3 trial?

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