Glucocorticoid receptor

BE0000794ProteinHumansNR3C1

Receptor for glucocorticoids (GC) (PubMed:27120390, PubMed:37478846). It is acted on by 111 drugs in DrugBank.

Gene name
NR3C1
UniProtKB entry
P04150Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
777 residues · 85,659 Da
Also known as
GR · GRL · Nuclear receptor subfamily 3 group C member 1

Resolves to

Protein
UniProtP04150UniProt nameGCR_HUMAN
Gene
HGNCHGNC:7978NCBI Gene2908GenBank31680GeneCardsNR3C1
Pharmacology
IUPHAR/GtoPdb625KEGGhsa:2908
Structure
PDB1M2ZPDB1NHZPDB1P93
Drugs

What you can answer from here — as of September 07, 2019

111DrugsApproved to experimental, with action, bond type and pharmacological action
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7Clinical trialsTrials of drugs acting on it, by phase and status
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41GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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468+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glucocorticoid receptor, how selective are they, and which programs against it are still in active trials?

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