Bepirovirsen

DB16202InvestigationalGene Therapies

IONIS-HBVRx is under investigation in clinical trial NCT04544956 (A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B).

Mechanism: Pharmacologically active on HBsAg and Toll-like receptor 8
Curator reviewed
Also known as: IONIS HBVRx · IONIS-HBVRx · Isis-gsk3rx
Code names: GSK-3228836 · ISIS-505358

Resolves to

Compound

UNIIZ87O6SM01NCAS1403787-62-1

Targets

Q69600S geneQ9NR97TLR8

What you can answer from here — as of July 08, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

12Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Bepirovirsen, and which of those have an active Phase 3 trial?

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