Lapaquistat

DB16215InvestigationalSmall molecule

Lapaquistat is under investigation in clinical trial NCT00256178 (Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.).

Mechanism: Pharmacologically active on Squalene synthase
Curator reviewed
Formula / weight: C₃₁H₃₉ClN₂O₈ · 603.11 g/mol (avg)

Resolves to

Compound

UNIIPEZ79BV72XCAS189059-71-0ChEMBLCHEMBL341976

Structure

InChIKeyHDGUKVZPMPJBFK-LEAFIULHSA-NSMILESCOC1=CC=CC([C@H]2O[C@H](CC(=O)N3CCC(CC(O)=O)CC3)C(=O)N(CC(C)(C)CO)C3=C2C=C(Cl)C=C3)=C1OC

Targets

P37268FDFT1

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Lapaquistat, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account