Modipafant

DB16237InvestigationalSmall molecule

Modipafant is under investigation in clinical trial NCT02569827 (Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore).

Mechanism: Pharmacologically active on Platelet-activating factor receptor
Curator reviewed
Formula / weight: C₃₄H₂₉ClN₆O₃ · 605.1 g/mol (avg)
Code names: UK-80067

Resolves to

Compound

UNII1DMI0E5023CAS122957-06-6ChEMBLCHEMBL2105829

Structure

InChIKeyODRYSCQFUGFOSU-SSEXGKCCSA-NSMILESCCOC(=O)C1=C(NC(C)=C([C@H]1C1=CC=CC=C1Cl)C(=O)NC1=NC=CC=C1)C1=CC=C(C=C1)N1C(C)=NC2=C1C=CN=C2

Targets

P25105PTAFR

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Modipafant, and which of those have an active Phase 3 trial?

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