Platelet-activating factor receptor

BE0005561ProteinHumansPTAFR

Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It is acted on by 14 drugs in DrugBank.

Gene name
PTAFR
UniProtKB entry
P25105Swiss-Prot
Cellular location
Cell membrane
Residues / weight
342 residues · 39,203 Da
Also known as
PAF-R · PAFR

Resolves to

Protein
UniProtP25105UniProt namePTAFR_HUMAN
Gene
HGNCHGNC:9582NCBI Gene5724GeneCardsPTAFR
Pharmacology
IUPHAR/GtoPdb334KEGGhsa:5724
Structure
PDB5ZKPPDB5ZKQPDB8XYD
Drugs

What you can answer from here — as of September 07, 2019

14DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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37+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Platelet-activating factor receptor, how selective are they, and which programs against it are still in active trials?

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