Osalmid
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Osalmid
- DrugBank Accession Number
- DB16273
- Background
Osalmid is under investigation in clinical trial NCT03670173 (Safety and Efficacy Assessments of Osalmid in Multiple Myeloma).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 229.235
Monoisotopic: 229.073893218 - Chemical Formula
- C13H11NO3
- Synonyms
- Osalmid
- External IDs
- L-1718
- NSC-93960
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 89741L759Z
- CAS number
- 526-18-1
- InChI Key
- LGCMKPRGGJRYGM-UHFFFAOYSA-N
- InChI
- InChI=1S/C13H11NO3/c15-10-7-5-9(6-8-10)14-13(17)11-3-1-2-4-12(11)16/h1-8,15-16H,(H,14,17)
- IUPAC Name
- 2-hydroxy-N-(4-hydroxyphenyl)benzamide
- SMILES
- OC1=CC=C(NC(=O)C2=CC=CC=C2O)C=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 4441
- ChEBI
- 31938
- ChEMBL
- CHEMBL389507
- ZINC
- ZINC000000001856
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 1, 2 Active Not Recruiting Treatment Multiple Myeloma (MM) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.409 mg/mL ALOGPS logP 2.15 ALOGPS logP 2.46 Chemaxon logS -2.8 ALOGPS pKa (Strongest Acidic) 7.92 Chemaxon pKa (Strongest Basic) -4.2 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 69.56 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 65.55 m3·mol-1 Chemaxon Polarizability 22.57 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-00di-1900000000-836e6fcb1f7e0f1a0c86 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-004l-5090000000-86e064557176045b7a79 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-00dl-7900000000-6fcdd0433d88a51c4457 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-0a6r-3940000000-8a54209ac048296098ea Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-0f76-9100000000-bc3f5dacba1e6b10fa7e Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-067i-9800000000-d3755b69cc288bcfd4fd Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 162.8344368 predictedDarkChem Lite v0.1.0 [M-H]- 151.47275 predictedDeepCCS 1.0 (2019) [M+H]+ 166.1577368 predictedDarkChem Lite v0.1.0 [M+H]+ 153.86833 predictedDeepCCS 1.0 (2019) [M+Na]+ 162.3241368 predictedDarkChem Lite v0.1.0 [M+Na]+ 159.79027 predictedDeepCCS 1.0 (2019)
Drug created at December 15, 2020 18:17 / Updated at February 21, 2021 18:55