Osalmid

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Osalmid
DrugBank Accession Number
DB16273
Background

Osalmid is under investigation in clinical trial NCT03670173 (Safety and Efficacy Assessments of Osalmid in Multiple Myeloma).

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 229.235
Monoisotopic: 229.073893218
Chemical Formula
C13H11NO3
Synonyms
  • Osalmid
External IDs
  • L-1718
  • NSC-93960

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Prevent Adverse Drug Events Today
Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events with our Clinical API
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!
See the data
Improve decision support & research outcomes with our structured adverse effects data.
See a data sample
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
89741L759Z
CAS number
526-18-1
InChI Key
LGCMKPRGGJRYGM-UHFFFAOYSA-N
InChI
InChI=1S/C13H11NO3/c15-10-7-5-9(6-8-10)14-13(17)11-3-1-2-4-12(11)16/h1-8,15-16H,(H,14,17)
IUPAC Name
2-hydroxy-N-(4-hydroxyphenyl)benzamide
SMILES
OC1=CC=C(NC(=O)C2=CC=CC=C2O)C=C1

References

General References
Not Available
ChemSpider
4441
ChEBI
31938
ChEMBL
CHEMBL389507
ZINC
ZINC000000001856

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1, 2Active Not RecruitingTreatmentMultiple Myeloma (MM)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.409 mg/mLALOGPS
logP2.15ALOGPS
logP2.46Chemaxon
logS-2.8ALOGPS
pKa (Strongest Acidic)7.92Chemaxon
pKa (Strongest Basic)-4.2Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count3Chemaxon
Polar Surface Area69.56 Å2Chemaxon
Rotatable Bond Count2Chemaxon
Refractivity65.55 m3·mol-1Chemaxon
Polarizability22.57 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-00di-1900000000-836e6fcb1f7e0f1a0c86
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-004l-5090000000-86e064557176045b7a79
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-00dl-7900000000-6fcdd0433d88a51c4457
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0a6r-3940000000-8a54209ac048296098ea
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0f76-9100000000-bc3f5dacba1e6b10fa7e
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-067i-9800000000-d3755b69cc288bcfd4fd
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-162.8344368
predicted
DarkChem Lite v0.1.0
[M-H]-151.47275
predicted
DeepCCS 1.0 (2019)
[M+H]+166.1577368
predicted
DarkChem Lite v0.1.0
[M+H]+153.86833
predicted
DeepCCS 1.0 (2019)
[M+Na]+162.3241368
predicted
DarkChem Lite v0.1.0
[M+Na]+159.79027
predicted
DeepCCS 1.0 (2019)

Drug created at December 15, 2020 18:17 / Updated at February 21, 2021 18:55