Florzolotau F-18

DB16297InvestigationalSmall molecule

PMPBB3 F-18 is under investigation in clinical trial NCT04305210 (Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18f-florbetapir (AV-45) PET Examination).

Mechanism: Pharmacologically active on Microtubule-associated protein tau
Curator reviewed
Formula / weight: C₂₀H₂₀FN₃O₂S · 384.46 g/mol (avg)
Code names: (18F) MNI-958 · APN-1607 F-18 · F-18 PMPBB3 · MNI-958 F-18 · PMPBB3 F-18

Resolves to

Compound

UNII51M993JIQ4CAS1565797-57-0

Structure

InChIKeyXXNYLYXTRMQXJS-CDLXMPELSA-NSMILESCNC1=CC=C(\C=C\C=C\C2=NC3=C(S2)C=C(OCC(O)C[18F])C=C3)C=N1

Targets

P10636MAPT

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Florzolotau F-18, and which of those have an active Phase 3 trial?

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