siG12D LODER

DB16329InvestigationalGene Therapies

siG12D LODER is under investigation in clinical trial NCT01676259 (A Phase 2 Study of Sig12d LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer).

Mechanism: Pharmacologically active on GTPase KRas
Curator reviewed
Also known as: Panc1 (krasgat)

Resolves to

Compound

UNIINNQ0PKZ9EV

Targets

P01116KRAS

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with siG12D LODER, and which of those have an active Phase 3 trial?

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