This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Sodium perchlorate is a competitive inhibitor of iodine uptake in the thyroid to protect from radiation or to diagnose congenital thyroid disorders.
- Generic Name
- Sodium perchlorate
- DrugBank Accession Number
- DB16608
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Sodium perchlorate (DB16608)
- Weight
- Average: 122.44
Monoisotopic: 121.9382805 - Chemical Formula
- ClNaO4
- Synonyms
- Natriumperchloraat
- Natriumperchlorat
- Perchlorate de sodium
- Perchloric acid, sodium salt
- External IDs
- 231-511-9
- UN-1502
- UN1502
Pharmacology
- Indication
Not Available
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Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Hyperthyroidism caused by amiodarone •••••••••••• •••••••• • ••••• Treatment of Hyperthyroidism caused by iodine •••••••••••• •••••••• • ••••• - Associated Therapies
- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
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- Irenat
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 97F4MTY3VA
- CAS number
- 7601-89-0
- InChI Key
- BAZAXWOYCMUHIX-UHFFFAOYSA-M
- InChI
- InChI=1S/ClHO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1
- IUPAC Name
- sodium perchlorate
- SMILES
- [Na+].[O-][Cl](=O)(=O)=O
References
- General References
- BASG: Irenat - Tropfen (Sodium Perchlorate) Oral Solution [Link]
- External Links
- ChemSpider
- 22668
- BindingDB
- 50102097
- ChEBI
- 132103
- ChEMBL
- CHEMBL1644700
- Wikipedia
- Sodium_perchlorate
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Solution / drops Oral 300 mg/ml - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 42.1 mg/mL ALOGPS logP -0.95 ALOGPS logP -0.098 Chemaxon logS -0.46 ALOGPS pKa (Strongest Acidic) -7.1 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 74.27 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 11.91 m3·mol-1 Chemaxon Polarizability 5.23 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 108.37514 predictedDeepCCS 1.0 (2019) [M+H]+ 111.17709 predictedDeepCCS 1.0 (2019) [M+Na]+ 119.361435 predictedDeepCCS 1.0 (2019)
Drug created at February 16, 2021 19:20 / Updated at May 22, 2021 06:02