MK-4541

DB17016ExperimentalSmall molecule

MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.

Mechanism: Pharmacologically active on Androgen receptor and 3-oxo-5-alpha-steroid 4-dehydrogenase
Curator reviewed
Formula / weight: C₂₂H₃₁F₃N₂O₃ · 428.496 g/mol (avg)
Also known as: 2,2,2-trifluoroethyl N-[(1S,3aS,3bS,5aR,9aR,9bS,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]carbamate
Code names: MK-4541

Resolves to

Compound

CAS796885-38-6

Structure

InChIKeyOGBFNZPDLOPGEO-OCWMMRLVSA-NSMILES[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])N(C)C(=O)C=C[C@]4(C)[C@@]3([H])CC[C@]12C)N=C(O)OCC(F)(F)F

Targets

P10275AR

What you can answer from here — as of July 08, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with MK-4541, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account