SY-5609

DB17099InvestigationalSmall molecule

SY-5609: Overview.

Mechanism: Pharmacologically active on Cyclin-dependent kinase 7
Curator reviewed
Formula / weight: C₂₃H₂₆F₃N₆OP · 490.471 g/mol (avg)
Also known as: (S)-7-(dimethylphosphoryl)-3-(2-((6,6-dimethylpiperidin-3-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)-1H-indole-6-carbonitrile · 1H-Indole-6-carbonitrile, 7-(dimethylphosphinyl)-3-[2-[[(3S)-6,6-dimethyl-3-piperidinyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]-
Code names: SY-5609

Resolves to

Compound

Structure

InChIKeyJDJOUBVVSQDIRC-AWEZNQCLSA-NSMILESCC1(C)CC[C@@H](CN1)NC1=NC=C(C(=N1)C1=CNC2=C1C=CC(C#N)=C2P(C)(C)=O)C(F)(F)F

Targets

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with SY-5609, and which of those have an active Phase 3 trial?

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