M-(18F)-fluorobenzylguanidine
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- M-(18F)-fluorobenzylguanidine
- DrugBank Accession Number
- DB17128
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 166.19
Monoisotopic: 166.088410001 - Chemical Formula
- C8H10FN3
- Synonyms
- 18F-meta-fluorobenzylguanidine
- Guanidine, ((3-(fluoro-18f)phenyl)methyl)-
- Meta-fluoro benzylguanidine F-18
- External IDs
- 18F-MFBG
- MFBG F-18
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- CD7WXM716P
- CAS number
- 156021-12-4
- InChI Key
- HNPHEZIYSZIWHH-RVRFMXCPSA-N
- InChI
- InChI=1S/C8H10FN3/c9-7-3-1-2-6(4-7)5-12-8(10)11/h1-4H,5H2,(H4,10,11,12)/i9-1
- IUPAC Name
- N-{[3-(¹⁸F)fluorophenyl]methyl}guanidine
- SMILES
- NC(=N)NCC1=CC([18F])=CC=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 396824
- ChEMBL
- CHEMBL4650354
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Active Not Recruiting Diagnostic Neuroblastoma (NB) 1 2 Not Yet Recruiting Diagnostic Neuroblastoma (NB) / Paragangliomas / Pheochromocytoma 1 1 Terminated Diagnostic Neural Crest Tumor / Neuroendocrine Tumors 1 1, 2 Recruiting Diagnostic Cardiovascular Disease (CVD) 1 0 Recruiting Diagnostic Neuroblastoma (NB) / Neuroendocrine Tumors / Paragangliomas / Pheochromocytoma 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.174 mg/mL ALOGPS logP 0.41 ALOGPS logP 0.91 Chemaxon logS -3 ALOGPS pKa (Strongest Basic) 12.11 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 61.9 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 55.46 m3·mol-1 Chemaxon Polarizability 16.37 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at November 17, 2022 22:13 / Updated at December 01, 2022 11:35