Orvacabtagene autoleucel

DB17231InvestigationalCell transplant therapies

Orvacabtagene autoleucel: Overview.

Mechanism
Curator reviewed
Also known as
JCARH125 CONSISTS OF HUMAN CULTURE EXPANDED GENETICALLY MODIFIED AUTOLOGOUS T CELLS FOR CELL-BASED GENE THERAPY. CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE SELF-INACTIVATING (SIN) LENTIVIRAL V · orva-cel
Code names
ET-140 · JCARH-125

Resolves to

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
2Clinical trialsPhase, status and sponsor resolved per trial
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which drugs share a target with Orvacabtagene autoleucel, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.

Create Account