Tumor necrosis factor receptor superfamily member 17

BE0010010ProteinHumansTNFRSF17

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. It is acted on by 27 drugs in DrugBank.

Gene name
TNFRSF17
UniProtKB entry
Q02223Swiss-Prot
Cellular location
Cell membrane
Residues / weight
184 residues · 20,165 Da
Also known as
B-cell maturation protein · BCM · BCMA

Resolves to

Protein
UniProtQ02223UniProt nameTNR17_HUMAN
Gene
HGNCHGNC:11913NCBI Gene608GeneCardsTNFRSF17
Pharmacology
IUPHAR/GtoPdb1889KEGGhsa:608
Structure
PDB1OQDPDB1XU2PDB2KN1
Drugs

What you can answer from here — as of August 06, 2020

27DrugsApproved to experimental, with action, bond type and pharmacological action
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22Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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63+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tumor necrosis factor receptor superfamily member 17, how selective are they, and which programs against it are still in active trials?

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