Divarasib

DB17488InvestigationalSmall molecule

Divarasib: Overview.

Mechanism
Curator reviewed
Also known as
1-((3S)-4-((7M)-7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((2S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one · 2-propen-1-one, 1-((3S)-4-((7R)-7-(6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl)-6-chloro-8-fluoro-2-(((2S)-1-methyl-2-pyrrolidinyl)methoxy)-4-quinazolinyl)-3-methyl-1-piperazinyl)-
Code names
GDC-6036 · RG 6330 · RO7435846

Resolves to

Compound
UNIIE6S21PVT91CAS2417987-45-0
Targets
P01116KRAS

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
13Clinical trialsPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Divarasib, and which of those have an active Phase 3 trial?

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