CGX-1321

DB17491InvestigationalSmall molecule

CGX-1321 is a porcupine inhibitor that affects Wnt production and can block Wnt downstream signaling.

Mechanism: Pharmacologically active on Protein-serine O-palmitoleoyltransferase porcupine
Curator reviewed
Code names: CGX-1321

Resolves to

Targets

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with CGX-1321, and which of those have an active Phase 3 trial?

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