Sirexatamab

DB17515InvestigationalProtein Based Therapies

Sirexatamab: Overview.

Mechanism
Curator reviewed
Also known as
Anti-dkk-1 monoclonal antibody ly2812176 · Dkk1-neutralizing monoclonal antibody dkn-01 · Immunoglobulin g4 (224-proline,233-alanine,234-alanine), anti-(human dickkopf-1) (human-mus musculus monoclonal dkn-01 .gamma.4-chain), disulfide with human-mus musculus monoclonal dkn-01 .kappa.-chain, dimer
Code names
DKN-01 · LY-2812176

Resolves to

Compound
UNIIRM898LZ4SICAS2414962-49-3
Targets
O94907DKK1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
14Clinical trialsPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Sirexatamab, and which of those have an active Phase 3 trial?

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