Andecaliximab

DB12296InvestigationalProtein Based Therapies

GS-5745 has been used in trials studying the treatment of Tumors, Breast Cancer, Crohn's Disease, Colorectal Cancer, and Pancreatic Cancer, among others.

Mechanism: Pharmacologically active on Matrix metalloproteinase-9
Curator reviewed
Also known as: Immunoglobulin g4, anti-(human gelatinase b) (human-mus musculus monoclonal gs-5745 heavy chain), disulfide with human-mus musculus monoclonal gs-5745 light chain, dimer
Code names: GS5745

Resolves to

Compound

UNII571045EIM4CAS1518996-49-0

Targets

P14780MMP9

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

381Drug interactionsStructured to mechanism, not free text

14Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Andecaliximab, and which of those have an active Phase 3 trial?

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