Denifanstat

DB17576InvestigationalSmall molecule

Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. Due to its antineoplastic activities, it is being investigated for various cancers.

Formula / weight: C₂₇H₂₉N₅O · 439.563 g/mol (avg)
Also known as: Benzonitrile, 4-(1-(4-cyclobutyl-2-methyl-5-(3-methyl-1h-1,2,4-triazol-5-yl)benzoyl)-4-piperidinyl)-
Code names: ASC-40 · TVB-2640

Resolves to

Compound

UNII4GF95B2LZACAS1399177-37-7ChEMBLCHEMBL3661754

Structure

InChIKeyBBGOSBDSLYHMRA-UHFFFAOYSA-NSMILESCC1=NC(=NN1)C1=CC(C(=O)N2CCC(CC2)C2=CC=C(C=C2)C#N)=C(C)C=C1C1CCC1

Targets

P49327FASN

What you can answer from here — as of February 28, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

16Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Denifanstat, and which of those have an active Phase 3 trial?

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