AEM-28

DB17642InvestigationalProtein Based Therapies

AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as homozygous familial hypercholesterolemia. It possesses anti-inflammatory properties.

Mechanism: Pharmacologically active on Apolipoprotein E
Curator reviewed
Also known as: AEM 28 · AEM28

Resolves to

Compound

UNIIV9526P2UXZ

Targets

P02649APOE

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with AEM-28, and which of those have an active Phase 3 trial?

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