Fazirsiran

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Fazirsiran
DrugBank Accession Number
DB17891
Background

Not Available

Type
Biotech
Groups
Investigational
Synonyms
  • Ads-001 free acid
  • ARO-AAT
  • Double stranded oligomer ADS-001 RNA interference-based liver targeted therapeutic
  • Fazirsiran
  • RNA, ((1'-DE(6-AMINO-9H-PURIN-9-YL))DA-(5'->5')-SP-AM-GM-CM-GM-UM-UM- UM-AM-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)C-AM- UM-GM-UM-UM-UM-AM-AM-CM-AM-(3'->3')-SP-(1'-DE(6-AMINO-9H-PURIN-9- YL))DA), 3'-(O-(CIS-4-((3S,8S)-17-((2-(ACE
  • TAK-999

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
V20IVC0OGQ
CAS number
2175009-08-0

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
3Enrolling by InvitationTreatmentAlpha-1 Anti-trypsin Deficiency1somestatusstop reasonjust information to hide
3RecruitingTreatmentAlpha-1 Anti-trypsin Deficiency2somestatusstop reasonjust information to hide
2Active Not RecruitingTreatmentAlpha-1 Anti-trypsin Deficiency1somestatusstop reasonjust information to hide
2CompletedTreatmentAlpha-1 Anti-trypsin Deficiency1somestatusstop reasonjust information to hide
1CompletedTreatmentAlpha-1 Anti-trypsin Deficiency1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at June 05, 2023 16:49 / Updated at June 08, 2023 19:01