Murizatoclax

DB17977InvestigationalSmall molecule

Murizatoclax: Overview.

Chemical structure of Murizatoclax
Formula / weight
C42H57ClN4O5S · 765.45 g/mol (avg)
Code names
AMG-397

Resolves to

Compound
UNIIBO0V7196L2CAS2245848-05-7ChEMBLCHEMBL4650225
Structure
InChIKeyBJTFTQIBRVBSBH-VCQPVEJUSA-NSMILESCO[C@]1(CN2CCN3CCCC[C@@H]3C2)\C=C\C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)C2=CC=C3OC[C@]4(CCCC5=CC(Cl)=CC=C45)CN(C[C@@H]4CC[C@@H]14)C3=C2
Targets
Q07820MCL1

What you can answer from here — as of April 23, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1Clinical trialPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Murizatoclax, and which of those have an active Phase 3 trial?

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