Golcadomide

DB18115InvestigationalSmall molecule

Golcadomide: Overview.

Mechanism: Pharmacologically active on Protein cereblon
Curator reviewed
Formula / weight: C₂₈H₃₀FN₅O₅ · 535.576 g/mol (avg)
Also known as: 2-[(3S)-2,6-dioxopiperidin-3-yl]-4-{[(2-fluoro-4-{[3-(morpholin-4-yl)azetidin-1-yl]methyl} phenyl) methyl]amino}-1H-isoindole-1,3(2H)-dione
Code names: CC -99282

Resolves to

Compound

Structure

InChIKeyNZYDBVQXOGPDDU-QHCPKHFHSA-NSMILESFC1=CC(CN2CC(C2)N2CCOCC2)=CC=C1CNC1=CC=CC2=C1C(=O)N([C@H]1CCC(=O)NC1=O)C2=O

Targets

What you can answer from here — as of September 12, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

25Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Golcadomide, and which of those have an active Phase 3 trial?

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