Berbamine

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DB18146ExperimentalSmall molecule

Berbamine: Overview.

Mechanism: Pharmacologically active on Signal transducer and activator of transcription 3
Curator reviewed
Formula / weight: C₃₇H₄₀N₂O₆ · 608.735 g/mol (avg)
Also known as: (+)-berbamine · 16h-1,24:6,9-dietheno-11,15-metheno-2h-pyrido(2',3':17,18)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolin-12-ol, 3,4,4a,5,16a,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-, (4as-(4ar*,16as*))- · 16h-1,24:6,9-dietheno-11,15-metheno-2h-pyrido(2',3':17,18)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolin-12-ol, 3,4,4a,5,16a,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-, (4as,16ar)- · 6,6',7-trimethoxy-2,2'-dimethylberbaman-12-ol · Berbaman-12-ol, 6,6',7-trimethoxy-2,2'-dimethyl-
Code names: NSC-121842

Resolves to

Compound

UNIIV5KM4XJ0WMCAS478-61-5ChEMBLCHEMBL504323ChEBI3063KEGGC09357

Structure

InChIKeyDFOCUWZXJBAUSQ-URLMMPGGSA-NSMILES[H][C@]12CC3=CC=C(OC4=CC(C[C@@]5([H])N(C)CCC6=CC(OC)=C(OC)C(OC7=CC1=C(CCN2C)C=C7OC)=C56)=CC=C4O)C=C3

Targets

P40763STAT3

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Berbamine, and which of those have an active Phase 3 trial?

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