PNT001

DB18375InvestigationalProtein Based Therapies

PNT001 is a humanized IgG4 S228P monoclonal antibody targeting the cis conformation of the phosphorylated Thr231-Pro232 motif in tau.

Mechanism: Pharmacologically active on Microtubule-associated protein tau
Curator reviewed
Code names: PNT-001

Resolves to

Targets

What you can answer from here — as of July 25, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with PNT001, and which of those have an active Phase 3 trial?

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