Efdoralprin alfa

DB18384InvestigationalProtein Based Therapies

Efdoralprin alfa is a recombinant human alpha-1 antitrypsin (AAT)-Fc fusion protein. It is being investigated as a restorative therapy in adults with AATD emphysema.

Mechanism: Pharmacologically active on Alpha-1-antitrypsin
Curator reviewed
Code names: INBRX-101 · SAR-447537

Resolves to

Compound

UNIITYK0A4WR1D

Targets

P01009SERPINA1

What you can answer from here — as of July 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Efdoralprin alfa, and which of those have an active Phase 3 trial?

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