Calmangafodipir

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DB18398InvestigationalSmall molecule

Calmangafodipir: Overview.

Mechanism: Pharmacologically active on Superoxide dismutase [Mn], mitochondrial and Superoxide dismutase
Curator reviewed
Formula / weight: C₁₁₀H₁₅₀Ca₄MnN₂₀O₇₀P₁₀ · 3397.468 g/mol (avg)
Also known as: Calcium,n,n'-1,2-ethanediylbis(n-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycine) manganese complexes trisodium trihydrogen manganate · Calmangafodipir (ca4mn(dpdp)5) · Pledox · Tetracalcium monomanganese penta(dipyridoxyl diphosphate)
Code names: PP100-01

Resolves to

Compound

UNIIN0JZU0WGU5CAS1401243-67-1

Structure

InChIKeyQAOJLUYEMFXJGX-UHFFFAOYSA-DSMILES

[Ca++].[Ca++].[Ca++].[Ca++].[Mn++].CC1=NC=C(COP(O)([O-])=O)C(CN(CCN(CC(O)=O)CC2=C(COP(O)([O-])=O)C=NC(C)=C2O)CC(O)=O)=C1O.CC1=NC=C(COP(O)([O-])=O)C(CN(CCN(CC(O)=O)CC2=C(COP(O)([O-])=O)C=NC(C)=C2O)CC(O)=O)=C1O.CC1=NC=C(COP(O)([O-])=O)C(CN(CCN(CC(O)=O)CC2=C(COP(O)([O-])=O)C=NC(C)=C2O)CC(O)=O)=C1O.CC1=NC=C(COP(O)([O-])=O)C(CN(CCN(CC(O)=O)CC2=C(COP(O)([O-])=O)C=NC(C)=C2O)CC(O)=O)=C1O.CC1=NC=C(COP(O)([O-])=O)C(CN(CCN(CC(O)=O)CC2=C(COP(O)([O-])=O)C=NC(C)=C2O)CC(O)=O)=C1O

Targets

P04179SOD2

What you can answer from here — as of October 04, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Calmangafodipir, and which of those have an active Phase 3 trial?

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