Elenestinib

DB18489InvestigationalSmall molecule

Elenestinib is a selective KIT inhibitor.

Mechanism: Pharmacologically active on Mast/stem cell growth factor receptor Kit
Curator reviewed
Formula / weight: C₂₇H₂₉FN₁₀O · 528.596 g/mol (avg)
Also known as: (S)-2-(4-(4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1H-pyrazol-1-yl)ethan-1-ol · 1H-Pyrazole-1-ethanol, 4-[4-[4-[5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]-2-pyrimidinyl]-1-piperazinyl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]- · 2-{4-[4-(4-{5-[(1S)-1-amino-1-(4- fluorophenyl)ethyl]pyrimidin-2-yl}piperazin-1- yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl]-1H-pyrazol-1- yl}ethan-1-ol · 4-[4-[4-[5-[(1S)-1-Amino-1-(4-fluorophenyl)ethyl]-2-pyrimidinyl]-1-piperazinyl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]-1H-pyrazole-1-ethanol
Code names: BLU-263

Resolves to

Compound

Structure

InChIKeyIPMARPMXSFFZFG-MHZLTWQESA-NSMILESC[C@](N)(C1=CC=C(F)C=C1)C1=CN=C(N=C1)N1CCN(CC1)C1=NC=NN2C=C(C=C12)C1=CN(CCO)N=C1

Targets

What you can answer from here — as of July 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Elenestinib, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.