Tildacerfont

DB18545InvestigationalSmall molecule

Tildacerfont is a corticotropin-releasing factor receptor-1 antagonist containing an unfused thiazole ring.

Chemical structure of Tildacerfont
Formula / weight
C20H26ClN5OS · 419.97 g/mol (avg)
Also known as
3-(5-chloro-2-morpholin-4-yl-thiazol-4-yl)-7-(1-ethyl-propyl)-2,5-dimethyl-pyrazolo(1,5-a)pyrimidine · Pyrazolo(1,5-a)pyrimidine, 3-(4-chloro-2-(4-morpholinyl)-5-thiazolyl)-7-(1-ethylpropyl)-2,5-dimethyl- · Pyrazolo(1,5-a)pyrimidine, 3-(4-chloro-2-(4-morpholinyl)-5-thiazolyl)-7-(1-ethylpropyl)-2,5-dimethyl-pyrazolo(1,3-a)pyrimidine

Resolves to

Compound
UNII09QCEV5481CAS1014983-00-6ChEMBLCHEMBL5095198
Structure
InChIKeyCLKXPWDYEYIPFS-UHFFFAOYSA-NSMILESCCC(CC)C1=CC(C)=NC2=C(C(C)=NN12)C1=C(Cl)SC(=N1)N1CCOCC1
Targets
P34998CRHR1

What you can answer from here — as of April 23, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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