Brigimadlin

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DB18578InvestigationalSmall molecule

Brigimadlin: Overview.

Mechanism: Pharmacologically active on E3 ubiquitin-protein ligase Mdm2
Curator reviewed
Formula / weight: C₃₁H₂₅Cl₂FN₄O₃ · 591.46 g/mol (avg)
Code names: BI 907828

Resolves to

Compound

UNII9A934ZAN94CAS2095116-40-6

Structure

InChIKeyAMTXDBGKYPDTTA-SJVQGLCSSA-NSMILES[H][C@]12CC3=C4C=CC(C(O)=O)=C(C)C4=NN3[C@@]1([H])[C@H](C1=CC=CC(Cl)=C1F)[C@@]1(N2CC2CC2)C(=O)NC2=CC(Cl)=CC=C12

Targets

Q00987MDM2

What you can answer from here — as of July 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

9Clinical trialsPhase, status and sponsor resolved per trial

16+ReferencesStructured and connected to the statements they support

Which drugs share a target with Brigimadlin, and which of those have an active Phase 3 trial?

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