Vasoactive intestinal peptide

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DB18634InvestigationalSmall molecule

Vasoactive intestinal peptide: Overview.

Mechanism: Pharmacologically active on Alpha adrenergic receptor
Curator reviewed
Formula / weight: C₁₄₇H₂₃₇N₄₃O₄₃S · 3326.83 g/mol (avg)
Also known as: His-ser-asp-ala-val-phe-thr-asp-asn-tyr-thr-arg-leu-arg-lys-gln-met-ala-val-lys-lys-tyr-leu-asn-ser-ile-leu-asn · Vasoactive intestinal peptide (human) · Vasoactive intestinal polypeptide
Code names: VIP

Resolves to

Compound

UNII6J2WVD66KRCAS37221-79-7ChEMBLCHEMBL1981592

Clinical / RWD

RxNorm1942960

Structure

InChIKeyVBUWHHLIZKOSMS-RIWXPGAOSA-NSMILES

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC1=CNC=N1)C(C)C)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(O)=O

Targets

P32241VIPR1

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

10Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Vasoactive intestinal peptide, and which of those have an active Phase 3 trial?

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