Vasoactive intestinal polypeptide receptor 1

BE0013137ProteinHumansVIPR1

G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed:35477937, PubMed:36385145, PubMed:8179610). It is acted on by 3 drugs in DrugBank.

Gene name
VIPR1
UniProtKB entry
P32241Swiss-Prot
Cellular location
Cell membrane
Residues / weight
457 residues · 51,547 Da
Also known as
PACAP type II receptor · PACAP-R-2 · PACAP-R2 · Pituitary adenylate cyclase-activating polypeptide type II receptor · VIP-R-1

Resolves to

Protein
UniProtP32241UniProt nameVIPR1_HUMAN
Gene
HGNCHGNC:12694NCBI Gene7433GeneCardsVIPR1
Pharmacology
IUPHAR/GtoPdb371KEGGhsa:7433
Structure
PDB1OF2PDB1OGTPDB3B3I
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Vasoactive intestinal polypeptide receptor 1, and which indications are they being tested in?

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