XEN-D0501

DB18673InvestigationalSmall molecule

XEN-D0501 is a tetrahydronaphthyl urea-based selective TRPV1 antagonist being investigated for the treatment of erythromelalgia.

Mechanism: Pharmacologically active on Transient receptor potential cation channel subfamily V member 1
Curator reviewed
Also known as: Tetrahydronaphthyl urea based selective TRPV1 antagonist
Code names: BAY-69-9426 · XEN-D0501

Resolves to

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

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3Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with XEN-D0501, and which of those have an active Phase 3 trial?

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