DNL343

DB18678InvestigationalSmall molecule

DNL343 is under investigation in clinical trial NCT05842941 (HEALEY ALS Platform Trial - Regimen G DNL343).

Mechanism: Pharmacologically active on Eukaryotic translation initiation factor 2 subunit 2
Curator reviewed
Code names: DNL-343

Resolves to

Compound

Targets

What you can answer from here — as of September 26, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with DNL343, and which of those have an active Phase 3 trial?

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