Temuterkib

DB18806InvestigationalSmall molecule

Temuterkib: Overview.

Mechanism: Pharmacologically active on Extracellular signal-regulated kinase (ERK)
Curator reviewed
Formula / weight: C₂₂H₂₇N₇O₂S · 453.57 g/mol (avg)
Code names: LY-3214996

Resolves to

Compound

Structure

InChIKeyJNPRPMBJODOFEC-UHFFFAOYSA-NSMILESCN1N=CC=C1NC1=NC=CC(=N1)C1=CC2=C(S1)C(C)(C)N(CCN1CCOCC1)C2=O

Targets

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

9Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Temuterkib, and which of those have an active Phase 3 trial?

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