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Allisartan isoproxil

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Identification

Generic Name
Allisartan isoproxil
DrugBank Accession Number
DB18880
Background

Allisartan isoproxil is under investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes).

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 553.02
Monoisotopic: 552.1887958
Chemical Formula
C27H29ClN6O5
Synonyms
  • 1H-IMIDAZOLE-5-CARBOXYLIC ACID, 2-BUTYL-4-CHLORO-1-((2'-(2H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL)-, (((1-METHYLETHOXY)CARBONYL)OXY)METHYL ESTER
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
DI4662MK4N
CAS number
947331-05-7
InChI Key
XMHJQQAKXRUCHI-UHFFFAOYSA-N
InChI
InChI=1S/C27H29ClN6O5/c1-4-5-10-22-29-24(28)23(26(35)37-16-38-27(36)39-17(2)3)34(22)15-18-11-13-19(14-12-18)20-8-6-7-9-21(20)25-30-32-33-31-25/h6-9,11-14,17H,4-5,10,15-16H2,1-3H3,(H,30,31,32,33)
IUPAC Name
SMILES
CCCCC1=NC(Cl)=C(N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NN=NN1)C(=O)OCOC(=O)OC(C)C

References

General References
Not Available
Human Metabolome Database
HMDB0248155
ChemSpider
57583156

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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4Active Not RecruitingPreventionMasked Hypertension1somestatusstop reasonjust information to hide
4RecruitingTreatmentAdverse Events / Blood Pressures / Cardiovascular Risk / Prehypertension / Type 2 Diabetes Mellitus1somestatusstop reasonjust information to hide
4RecruitingTreatmentAtrial Fibrillation / Hypertension1somestatusstop reasonjust information to hide
4WithdrawnTreatmentBlood Pressures / Type 2 Diabetes Mellitus1somestatusstop reasonjust information to hide
3CompletedTreatmentHypertension, Essential Hypertension1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 26, 2024 22:00 / Updated at June 27, 2024 01:29