INCB-086550

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DB18901InvestigationalSmall molecule

INCB-086550 is under investigation in clinical trial NCT04629339 (Study of INCB086550 in Select Solid Tumors).

Mechanism: Pharmacologically active on Programmed cell death 1 ligand 1
Curator reviewed
Formula / weight: C₄₁H₃₉N₇O₄ · 693.808 g/mol (avg)
Also known as: 3-PYRROLIDINECARBOXYLIC ACID, 1-((7-CYANO-2-(3'-((3-(((3R)-3-HYDROXY-1-PYRROLIDINYL)METHYL)-1,7-NAPHTHYRIDIN-8-YL)AMINO)-2,2'-DIMETHYL(1,1'-BIPHENYL)-3-YL)-5-BENZOXAZOLYL)METHYL)-, (3R)-
Code names: INCB-086550

Resolves to

Compound

UNIIT8B91S15VFCAS2230911-59-6

Structure

InChIKeyQARLNMDDSQMINK-BVRKHOPBSA-NSMILESCC1=C(NC2=NC=CC3=CC(CN4CC[C@@H](O)C4)=CN=C23)C=CC=C1C1=CC=CC(C2=NC3=CC(CN4CC[C@H](C4)C(O)=O)=CC(C#N)=C3O2)=C1C

Targets

Q9NZQ7CD274

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with INCB-086550, and which of those have an active Phase 3 trial?

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