Ponsegromab

DB18943InvestigationalProtein Based Therapies

Ponsegromab is under investigation in clinical trial NCT05492500 (A Study of Ponsegromab in People With Heart Failure).

Mechanism
Curator reviewed
Also known as
Immunoglobulin g1 (237-alanine,238-alanine,240-alanine), anti-(human growth differentiation factor 15) (human-mus musculus monoclonal pf-06946860 .gamma.1-chain), disulfide with human-mus musculus monoclonal pf-06946860 .kappa.-chain, dimer
Code names
PF-06946860

Resolves to

Compound
UNIIGXA6PF0254CAS2368950-15-4
Targets
Q99988GDF15

What you can answer from here — as of July 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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7Clinical trialsPhase, status and sponsor resolved per trial
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4+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Ponsegromab, and which of those have an active Phase 3 trial?

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