Gotistobart

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Gotistobart
DrugBank Accession Number
DB19100
Background

Gotistobart is under investigation in clinical trial NCT05671510 (ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors).

Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
  • Gotistobart
External IDs
  • BNT316
  • ONC 392
  • ONC-392
  • ONC392

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
4R46M31XXP
CAS number
2226344-78-9

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
3RecruitingTreatmentNon-Small Cell Lung Cancer (NSCLC)1somestatusstop reasonjust information to hide
2RecruitingTreatmentFallopian Tube Cancer / High Grade Serous Adenocarcinoma of Ovary / Ovarian Cancer / Primary Peritoneal Carcinoma1somestatusstop reasonjust information to hide
1, 2RecruitingTreatmentAdenocarcinomas of the Gastroesophageal Junction / Adenoid Cystic Carcinoma / Advanced Solid Tumors / Cervical Cancer / Esophageal Cancer / Gastric Cancer / Metastatic Breast Cancer / Metastatic Colorectal Cancer (CRC) / Metastatic Head and Neck Carcinoma / Metastatic Melanoma / Metastatic Prostate Cancer / Metastatic Renal Cell Carcinoma ( mRCC) / Non-Small Cell Lung Cancer (NSCLC) / Ovarian Cancer / Pancreatic Cancer / Salivary Gland Cancers / Sarcomas / Small Cell Lung Cancer (SCLC) / Urothelial Carcinoma1somestatusstop reasonjust information to hide
1, 2RecruitingTreatmentMetastatic Castration-Resistant Prostate Cancer (mCRPC)1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at July 03, 2024 21:12 / Updated at July 04, 2024 03:36