JNJ-55308942

DB19110InvestigationalSmall molecule

JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).

Mechanism: Pharmacologically active on P2X purinoceptor 7
Curator reviewed
Formula / weight: C₁₇H₁₂F₅N₇O · 425.323 g/mol (avg)
Also known as: ((6S)-1-(5-FLUORO-2-PYRIMIDINYL)-1,4,6,7-TETRAHYDRO-6-METHYL-5H-1,2,3-TRIAZOLO(4,5-C)PYRIDIN-5-YL)(3-FLUORO-2-(TRIFLUOROMETHYL)-4-PYRIDINYL)METHANONE · (S)-(3-Fluoro-2-(trifluoromethyl)pyridin-4-yl)(1-(5-fluoropyrimidin-2-yl)-6-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridin-5(4H)-yl)methanone · 5-fluoro-2-[(6S)-5-[3-fluoro-2-(trifluoromethyl)pyridine-4-carbonyl]-6-methyl-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridin-1-yl]pyrimidine · METHANONE, ((6S)-1-(5-FLUORO-2-PYRIMIDINYL)-1,4,6,7-TETRAHYDRO-6-METHYL-5H-1,2,3-TRIAZOLO(4,5-C)PYRIDIN-5-YL)(3-FLUORO-2-(TRIFLUOROMETHYL)-4-PYRIDINYL)-
Code names: JNJ-55308942

Resolves to

Compound

Structure

InChIKeyLMDWZBQISRTEBH-QMMMGPOBSA-NSMILESC[C@H]1CC2=C(CN1C(=O)C1=CC=NC(=C1F)C(F)(F)F)N=NN2C1=NC=C(F)C=N1

Targets

What you can answer from here — as of July 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with JNJ-55308942, and which of those have an active Phase 3 trial?

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