Ovatodiolide

DB19264InvestigationalSmall molecule

Ovatodiolide is under investigation in clinical trial NCT04220411 (A Study for AR100DP1 in Mild to Moderate Atopic Dermatitis (AD)).

Mechanism: Pharmacologically active on Catenin beta-1
Curator reviewed
Formula / weight: C₂₀H₂₄O₄ · 328.408 g/mol (avg)
Also known as: (3as,6e,13s,15e,16ar)-3a,4,5,8,9,13,14,16a-octahydro-6,15-dimethyl-3-methylene-11h-13,10-methenofuro(2,3-f)oxacyclopentadecin-2,11(3h)-dione · (3e,12e)-3,12-dimethyl-8-methylene-6,18-dioxa-tricyclo(14.2.1.0.5,9)nonadeca-3,12,16(19)-triene-7,17-dione · 11h-13,10-methenofuro(2,3-f)oxacyclopentadecin-2,11(3h)-dione, 3a,4,5,8,9,13,14,16a-octahydro-6,15-dimethyl-3-methylene-, (3as,6e,13s,15e,16ar)-
Code names: AR100 · AR-100DP1 · AR-100 (OV) · NSC-156130 · NSC-272353

Resolves to

Compound

Structure

InChIKeyKTYZKXFERQUCPX-SIKGVNBJSA-NSMILES[H][C@]12C\C(C)=C\[C@@]3([H])OC(=O)C(=C)[C@]3([H])CC\C(C)=C\CCC(=C1)C(=O)O2

Targets

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Ovatodiolide, and which of those have an active Phase 3 trial?

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